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                 A83. Eastern equine encephalitis



Eastern equine encephalitis (Triple E) is an illness caused by a virus that comes from an infected mosquito bite. Most people who are infected have no symptoms, but some may develop fever, headaches, and vomiting. Symptoms occur within 4-10 days of being infected and most recover in 1-2 weeks. A small number will develop swelling of the brain and severe neurological symptoms that can be permanent. Triple E can also lead to coma and death. This condition is caused by a type of arbovirus and is transmitted by a mosquito which has bitten an infected bird or reptile. Diagnosis is based on the symptoms, specific findings in the blood, and occasionally by an MRI of the brain. There is no specific treatment for Triple E. It is managed by taking care of the symptoms. Prevention includes avoiding mosquito bites and controlling mosquito populations.



Symptoms

The following list includes the most common signs and symptoms in people with eastern equine encephalitis (Triple E) virus infections. These features may be different from person to person. Some people may have more symptoms than others and symptoms can range from mild to severe. This list also does not include every symptom or feature that has been described in this condition.

  • Fever
  • Chills
  • Fatigue
  • Vomiting
  • Focal neurological signs
  • Cranial nerve palsies (weakness or loss of function of a large nerve)
  • Coma.

Most people who are infected with the Triple E virus do not get sick. Some develop flu-like symptoms (fever, chills, vomiting) within 4-10 days after being infected. If the infection reaches the brain it can lead to seizures, coma and sometimes, death. Some people may have brain damage that leads to paralysis,  or changes in behavior or personality

Causes

Eastern equine encephalitis (Triple E) is caused by a type of called virus an arbovirus.  Humans catch this virus through a bite from certain types of mosquitos

Treatment

Eastern equine encephalitis (Triple E) is diagnosed in someone who is sick through tests that look for evidence of the triple E virus in blood, tissue or other body fluids.  Sometimes Imaging studies, such as an  MRI or C T scan can be helpful

Diagnosed

Eastern equine encephalitis (Triple E) is diagnosed in someone who is sick through tests that look for evidence of the triple E virus in blood, tissue or other body fluids.  Sometimes imaging studies, such as an MRI or CT scan can be helpful.

Eastern equine encephalitis virus (EEE) is transmitted to humans by the bite of an infected mosquito. Eastern equine encephalitis (EEE) is a rare illness in humans, and only a few cases are reported in the United States each year. Most cases occur in the Atlantic and Gulf Coast states. Most persons infected with EEE have no apparent illness. Severe cases of EEE (involving encephalitis, an inflammation of the brain) begin with the sudden onset of headache, high fever, chills, and vomiting. The illness may then progress into disorientation, seizures, or coma. EEE is one of the most severe mosquito-transmitted diseases in the United States with approximately 33% mortality and significant brain damage in most survivors. There is no specific treatment for EEE; care is based on symptoms. You can reduce your risk of being infected with EEE by using insect repellent, wearing protective clothing, and staying indoors while mosquitoes are most active. If you think you or a family member may have EEE, it is important to consult your healthcare provider for proper diagnosis.


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